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Esophageal carcinoma is the 6th most common cause of cancer with Barrett’s esophagus contributing to be the biggest risk factor. A randomized trial performed studied role of high-dose PPI and aspirin for  improving outcomes in patients with Barrett’s esophagus. Patients with 1 cm or more of Barrett’s esophagus at 84 different centers in UK and Canada  were randomized 1:1:1:1  using a computerized schedule to receive high-dose ( 40 mg ...

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In adults the common cause of chronic abdominal pain: Carcinoma In children, the common cause of chronic abdominal pan: Irritable bowel syndrome References: 1. Chronic Abdominal pain in children. Pediatrics 2005;115;812 2. Chronic Abdominal pain. Kapural 2015. ISBN: 9781-4939-1991-8

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