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Definition: It is a Hormonal Disorder that develops due to hypersecretion of GH in adulthood, after the epiphyseal closure of bones, which cause an increase in size (girth) of bones, including that of face, hands and feet Incidence: Annual incidence= 3-4cases/million population Prevalence= 60-70 cases/million population Male=female Mean age of presentation Males-42yrs, Females-44yrs Pathogenesis: There are several reasons for overproduction of GH. ...

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A meta analysis was recently done to assess the diagnostic accuracy of POC BNP testing in patients with chronic heart failure, especially in an ambulatory setting. This was against any relevant standard of care interventions like ECHO, clinical examination or combination of both. At thresholds of >100 pg/ml the sensitivity of BNP was 0.95. At levels <100, it ranged from 0.46 to 0.97 and specificity of 0.31 to 0.98. So ...

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Esophageal carcinoma is the 6th most common cause of cancer with Barrett’s esophagus contributing to be the biggest risk factor. A randomized trial performed studied role of high-dose PPI and aspirin for  improving outcomes in patients with Barrett’s esophagus. Patients with 1 cm or more of Barrett’s esophagus at 84 different centers in UK and Canada  were randomized 1:1:1:1  using a computerized schedule to receive high-dose ( 40 mg ...

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APGAR score stands for Appearance, Pulse, Grimace, Activity and Respiration. An APGAR score of <7 at 5 mins requires repeated scoring every 5 mins for upto 20 mins to check for improvement.

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