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April 15 2015

Ribavirin

What are the teratogenic effects of Ribavirin?

Neuros
Neuros
April 15 2015 #

Ribavirin is a drug that is used to treat Hepatitis C. This drug however has teratogenic (Category X) effects and is contraindicated in females who are pregnant and also males whose partners are pregnant. 

Some of the teratogenic effects are:

  1. Torticollis
  2. Hypospadias
  3. Polydactyly
  4. Neonatal Tooth
  5. Ventral septal defect
  6. Death

References:

  1. PubMed: The Ribavirin Pregnancy Registry; Findings after 5 years of enrollment 2003-2009 (Accessed 15 Apr 2015) 
  2. Drugs.com: Ribavirin (Accessed 15 Apr 2015) 
  3. American Family Physicians: Using Pegylated Interferon and Ribavirin to Treat Patients with Chronic Hepatitis C (Accessed 15 Apr 2015) 

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