Pharmacology

Pharmacology

Study of drugs and its interaction with the human body.

tuqa commented on the question

Give reason for combination of sulphamethoxazole and trimethoprim.

Give reason for combination of sulphamethoxazole and trimethoprim.

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tuqa
August 24 2015 #

synergistic affect

to prolong the halftime

to widen the spectrum

tuqa commented on the question

Cotrimoxazole

Cotrimoxazole

Mechanism of action

Adverse effects

tuqa
August 24 2015 #

it is mostly used in DS ( double strength ) tablet ,

tuqa commented on the question

Sulphonamides are not effective in presence of pus. Why?

Sulphonamides are not effective in presence of pus. Why?

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tuqa
August 24 2015 #

it increases the substrate ( PABA) so the inhibition by sulfa drugs will be inhibited

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tuqa commented on the note

what is the effect of bile acid sequestrants like colestamine, colestipol on triglycerides and the mechanism???

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tuqa
August 24 2015 #

decrease TAGs and helps in increasing bile losing in bowel along with lipids m so that decrease lipid absorption , because bile is synthesis in 24 hr is very minimal that cant help in fat absorption , so mainly bil...Read More

tuqa commented on the question

Sulfonylurea

Write a short note on Sulfonylurea

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tuqa
August 24 2015 #

for DM to release insulin with k channel interaction

Neuros

Neuros commented on the question

anti malarial

Why 45 mg of primaquine is given in plasmodium falciparum malaria???

Neuros
Neuros
April 22 2015 #

Primaquine plays a major role in reducing malarial transmission by its gametocytocidal action. To avoid side effects, the safe dosage recommended is 0.25mg base/kgSource: WHO website 

Neuros

Neuros commented on the question

Uses of digoxin

Uses of digoxin

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Neuros
Neuros
April 21 2015 #

The most common indication is Atrial fibrillation and atrial flutter. Compared to previously, dignoxin is no longer used as the first choice of drug in treating heart failure.

Neuros

Neuros commented on the question

Digoxin

What factors contribute to digoxin toxicity?

Neuros
Neuros
April 20 2015 #

The following factors contribute to digoxin toxicity: [1] Body Characteristics:
  • Advanced age
  • Small BMI (women)
[2] Medical Conditions:
  • Myocardial Ischemia
  • Hypothyroidism
  • Renal insufficiency
  • Hyperthyroidism
  • Meta...
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Neuros

Neuros started a question

Digoxin

What factors contribute to digoxin toxicity?

Neuros

Neuros commented on the question

Ribavirin

What are the teratogenic effects of Ribavirin?

2 people liked this
Neuros
Neuros
April 15 2015 #

Ribavirin is a drug that is used to treat Hepatitis C. This drug however has teratogenic (Category X) effects and is contraindicated in females who are pregnant and also males whose partners are pregnant.  Some of th...Read More

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Neuros

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Ribavirin

What are the teratogenic effects of Ribavirin?

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arshad commented on the photo

13 people liked this
arshad
April 07 2015 #

well

jimshad commented on the question

Danazol

Write a short note on Danazol

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jimshad
October 07 2014 #

first drug specifically used to treat endometriosis

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jimshad commented on the question

Sulfonylurea

Write a short note on Sulfonylurea

3 people liked this
jimshad
October 05 2014 #

some classify glimpiride as third generation....

suhel shared a note

what is the effect of bile acid sequestrants like colestamine, colestipol on triglycerides and the mechanism???

tuqa liked this
Neuros

Neuros commented on the question

Sulfonylurea

Write a short note on Sulfonylurea

3 people liked this
Neuros
Neuros
April 03 2014 #

Sulfonylureas are oral hypoglycemic drugs used for treatment of diabetes. These include: First Generation Sulfonylureas
  • Chlorpropamide
  • Tolbutamide
Second Generation Sylfonylureas
  • Glyburide
  • Gliclazide
  • Glipizide
  • Glim...
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Neuros

Neuros commented on the question

Sulphonamides are not effective in presence of pus. Why?

Sulphonamides are not effective in presence of pus. Why?

4 people liked this
Neuros
Neuros
April 03 2014 #

P-aminobenzoic acid is required by bacteria to synthesize folic acid. Sulfanomides are structural analogues of PABA and thus inhibit the synthesis of folic acid.  Pus contains purines,thymidine & PABA which:
  1. Causes ...
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Neuros

Neuros commented on the question

Neuropathic Pain

What are some of the neuropathic conditions that are treated with Tricyclic antidepressants

jimshad liked this
Neuros
Neuros
April 03 2014 #

Painful conditions that are treated with Tricyclic antidepressants:

  1. Diabetic neuropathy
  2. Postherpatic neualgia
  3. Migraine headaches
  4. Cancer related neuralgia
  5. Trigeminal neuralgia

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Neuros

Neuros started a question

Neuropathic Pain

What are some of the neuropathic conditions that are treated with Tricyclic antidepressants

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Neuros

Neuros commented on the question

Danazol

Write a short note on Danazol

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Neuros
Neuros
March 23 2014 #

Danazol is an adrogen, that binds to nuclear receptors in the target cells. This hormone-receptor comple binds to DNA and stimulates synthesis of specific RNAs and proteitns. Uses:
  1. Endometriosis: used in the treatmen...
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