Biochemistry

Biochemistry

Study of chemical processes in the human body.
Medical Guru

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Alpha Fetoprotein

Write a short note on alpha fetoprotein.

Medical Guru
Medical Guru
May 04 2015 #

Alpha fetoprotein is a substance that is made by the fetal liver, and whose levels are high right after birth. But afterwards, the levels decrease. But there are certain medical conditions in which the level of AFP in...Read More

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Synthesis of gamma amino levulinate.

Write briefly on (Synthesis of gamma-amino levulinate).

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glycolysis

can anyone describe glycolysis ? with its energy sheet !!

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Neuros Team

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Glutamine dehydrogenase(GLDH)

Write the reaction catalysed by "Glutamine dehydrogenase" and add a note on its significance.

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Neuros Team
Neuros Team
August 23 2013 #

Glutamine Dehydrogenase (GLDH) is an enzyme that converts glutamate to alpha-ketoglutarate and ammonia.it is present in mitochondria. Glutamate + (NADP+) + H2O -------- NH4 + a-ketoglutarate + (H+) Significance: It ...Read More

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Neuros Team

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Creatinine

Write a short note on steps in formation of creatinine in the body.

Neuros Team
Neuros Team
August 21 2013 #

Creatinie is synthesized in liver and kidneys. Formation of creatinie involves two steps.
  1. Formation of Guanidinoacetate: it is first step. aminoacids glycine and arginine react together and form  ornithine and guani...
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Neuros

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Carnitine

Write a short note on carnitine and its role in oxidation of fatty acids.

Neuros
Neuros
August 20 2013 #

Carnitine is a quarternary ammonium compounds biosynthesized from the amino acids lysine and methionine. Role of carnitine carrier system:
  • The inner mitochondrial membrane is impermeable to fatty acids.
  • A specialized...
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Aciduria

Write a short note on methyl malonyl aciduria.

Neuros Team
Neuros Team
August 17 2013 #

It is an autosomal recessive disorder of animo acid metabolism. It involves a defect in the conversion of methylmalonyl-coA to succinyl CoA due to defect in enzyme methylmalonyl CoA mutase.   METHYLMALONIC ACIDEMIA i...Read More

Neuros Team

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Porphyria

What is porphyria?  Classify different types of porphyrias. Give the enzyme defects and biological findings.

Neuros Team
Neuros Team
August 16 2013 #

The porphyrias are a group of diseases caused by abnormalities in the pathway of biosynthesis of the various porphyrins. Porphyrias are classfied into two types:
  1. Erythrocytic : Enzyme defect in erythrocytes.
  2. Heaptic:...
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Neuros Team

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Urea Cycle

Describe the reactions of urea cycle. Mention the normal blood urea level and add a note on its clinical significance. Mention metabolic disorders of urea cycle.

Neuros Team
Neuros Team
August 16 2013 #

Urea cycle: Convertion of Ammonia (NH3) into Urea ((NH2)2 CO) is called Urea cycle. in a single turn of cycle
  • 2 ammonia (NH3) molecules are reduced.
  • 1 carbondioxide (CO2) molecule is reduced.
  • 1 urea ((NH2)2 CO)molecule...
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Creatinine & Urea

Write the normal serum levels of:

Creatinine

Urea.

Neuros Team
Neuros Team
August 14 2013 #

Normal serum levels of  1-Creatinine:
  • 0.9-1.3 mg/dl or 0.6-1.2 mg/dl adult male
  • 0.6-1.1 mg/dl adult female
2-Serum Urea, (BUN)
  • 8-24 mg/dl adult male
  • 6-21 mg/dl adult female.
Author: Dr rameesa References:
  1. Kid...
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Neuros Team

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Calmodulin

Write a short note on calmodulin.

Neuros Team
Neuros Team
August 12 2013 #

Calmodulin is a calcium-dependent regulatory protein.  Name: Calmodulin or CaM ( calcium-modulated protein) Molecular mass: It has a molecular weight of 17-kDa. Structure: It is similar to protein troponin C (pre...Read More

Neuros Team

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Electrolytes

Mention the normal plasma values of the following electrolytes:

Serum sodium

Serum potassium

Serum calcium

Serum chloride.

Neuros Team
Neuros Team
August 10 2013 #

  1. serum sodium:          135-145 mEq/l
  2. serum potassium:      3.5-5.0 mEq/l
  3. serum calcium:          8.4-10.2 mEq/dl
  4. serum chloride:         98-108 mEq/l
Author: Dr rameesa References Read More

Neuros

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Glycolysis

Name the regulatory hormones of glycolysis?

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Neuros
Neuros
August 08 2013 #

  1. Glucokinase
  2. Phosphofructokinase
  3. Pyruvate kinase

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Amino Acids

Write the amino acids from which the following compounds are formed:

Adrenaline

GABA

Melanin

Histamine.

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Neuros Team
Neuros Team
August 07 2013 #

  1. Adrenaline: from  phenylalanine and tyrosine
  2. GABA (gamma-Aminobutyric acid, cheif neurotransmitter it is synthesized in brain because it cannot penetrate bloodbrain barrier):from Glutamate 
  3. Melanin( responsible for ...
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Neuros Team

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What is the salvage pathway for Purine synthesis?

What is the salvage pathway for Purine synthesis?

Neuros Team
Neuros Team
August 06 2013 #

Salvage pathway is a pathway that reuses nucleosides and bases which are formed during degradation  or repairation of DNA or RNA.
  • It is far more energy conserving than "de novo synthesis"
  • These bases are really toxi...
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Nithin Chand started a question

What is the salvage pathway for Purine synthesis?

What is the salvage pathway for Purine synthesis?

Abdul Aziz

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Genetics

Can anyone recommend a good book for medical genetics? I can't seem to find any!

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Abdul Aziz
Abdul Aziz
July 30 2013 #

I've finished MBBS, and am preparing for PG entrance

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Neuros

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Genetics

Can anyone recommend a good book for medical genetics? I can't seem to find any!

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Neuros
Neuros
July 26 2013 #

Depends on what course you are studying. Let us know so we can suggest

Abdul Aziz

Abdul Aziz started a question

Genetics

Can anyone recommend a good book for medical genetics? I can't seem to find any!

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Effects of Hypoglycemia

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